Mucolytic to facilitate expectoration by reducing sputum viscosity in the case of cystic fibrosis.

By mouth
Child 6–11 years (body-weight up to 30 kg): 50/75 mg, to be taken in the morning and, Ivacaftor 75 mg to be taken in the evening (about 12 hours apart).
Child 6–11 years (body-weight 30 kg and above): 100/150 mg, to be taken in the morning and, Ivacaftor 150 mg to be taken in the evening (about 12 hours apart).
Child 12–17 years: 100/150 mg, to be taken in the morning and, Ivacaftor 150 mg to be taken in the evening (about 12 hours apart).
Adult: 100/150 mg, to be taken in the morning in combination with Ivacaftor 150 mg in the evening.

Non-sedating antihistamine.

Seasonal allergic rhinitis
• Child 6–11 years: 30 mg, twice daily.
• Over 12 years: 120 mg, once daily.

By inhalation of nebulised solution for asthma
• Over 12 years: 5–10 mg 2–4 times daily, additional doses may be necessary in severe acute asthma.

By inhalation of nebulised solution for moderate to severe acute asthma
• Child 1 month–4 years: 5 mg, repeat every 20–30 minutes or as required
• Child 5–11 years: 5–10 mg, repeat every 20–30 minutes or as required
• Over 12 years: 10 mg, repeat every 20–30 minutes or as required

Short-acting selective beta2 agonist.

By inhalation of nebulised solution for asthma
• Over 12 years: 5–10 mg 2–4 times daily, additional doses may be necessary in severe acute asthma.

By inhalation of nebulised solution for moderate to severe acute asthma
• Child 1 month–4 years: 5 mg, repeat every 20–30 minutes or as required
• Child 5–11 years: 5–10 mg, repeat every 20–30 minutes or as required
• Over 12 years: 10 mg, repeat every 20–30 minutes or as required

By inhalation of nebulised solution for asthma
• Over 12 years: 5–10 mg 2–4 times daily, additional doses may be necessary in severe acute asthma.

By inhalation of nebulised solution for moderate to severe acute asthma
• Child 1 month–4 years: 5 mg, repeat every 20–30 minutes or as required
• Child 5–11 years: 5–10 mg, repeat every 20–30 minutes or as required
• Over 12 years: 10 mg, repeat every 20–30 minutes or as required

Trainhaler is a placebo-like MDI training system which can be used in conjunction with a Flo-Tone trainer to provide flow and co-ordination coaching.

Stockists: Clement Clarke, Williams Medical Supplies.

Long-acting muscarinic antagonist, Long-acting selective beta2 agonist with corticosteroid.

Adult for moderate COPD: one inhalation once daily – to be taken at the same time each day.

By deep intramuscular injection into the gluteal for suppression of inflammatory and allergic disorders
• Adult: 40 mg (maximum dose of 100 mg), repeated if necessary.

Long-acting muscarinic receptor antagonist, long-acting selective beta2 agonist with corticosteroid.

Trimbow 87/5/9 for moderate to severe COPD or asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow 172/5/9 for asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow NEXThaler 88/5/9 for moderate to severe COPD 
Adult: 2 inhalations twice daily.