Respiratory Handbook
For UK audiences

The professional's guide to product selection

Resp-Ease - Hypertonic sodium chloride
Mucolytics Hypertonic sodium chloride Venture Healthcare

Resp-Ease - Hypertonic sodium chloride

Mucolytic to facilitate expectoration by reducing sputum viscosity.

4ml nebuliser solution up to twice daily undiluted. It can be used in conjunction with chest hygiene clearance which has been assessed in secondary care.

Indications

Non-CF bronchiectasis for use prior to airway clearance to increase sputum yield, reduce sputum viscosity and increase ease of expectoration. 

Complex COPD & complex asthma patients where usual treatment (systemic hydration, physiotherapy, airway clearance, mucolytics/nebulised solutions) are ineffective

 

Nebulised hypertonic sodium chloride solution (3–7%) is used to mobilise lower respiratory tract secretions in mucous consolidation (e.g. cystic fibrosis).

Nebulised hypertonic sodium chloride solution (3%) is used for mild to moderate acute viral bronchiolitis in infants.

Recipients may benefit from the use of an inhaled bronchodilator before treatment with hypertonic sodium chloride to reduce the risk of temporary irritation, such as coughing, hoarseness, or reversible bronchoconstriction, which may occur.

Preparations Available

Nebuliser solution

Sizes Available

Nebuliser solution
Resp-Ease 3%, 60 × 4 ml
Resp-Ease 6%, 60 × 4 ml
Resp-Ease 7%, 60 × 4 ml

Price

Mucolytics

All Mucolytics
Carbocisteine - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Carbocisteine - AAH Pharmaceuticals Ltd

Reduction of sputum viscosity. 

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Accord Healthcare Ltd
Accord Healthcare

Carbocisteine - Accord Healthcare Ltd

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Esteve
Esteve

Carbocisteine - Esteve

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Typharm
Typharm

Carbocisteine - Typharm

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Viatrus
Viatrus UK Healthcare Ltd

Carbocisteine - Viatrus

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Osmohale - Mannitol - Chapper Healthcare
Chapper Healthcare

Osmohale - Mannitol - Chapper Healthcare

Mucolytic 

Osmohale is used for an indirect osmotic bronchial challenge test which can be used to identify bronchial hyperresponsiveness, a clinical feature of some respiratory conditions such as asthma.

Contraindications: Use with caution in renal impairment and to avoid in pregnancy. The Osmohale test should not be used in patients below 6 years of age due to their inability to provide reproducible spirometric measurements.

There is limited information on the use of Osmohale in patients 6-18 years of age therefore Osmohale is not recommended in this population.

Dose: See manufacturers’ instructions for more information. The test should be repeated until the patient has a positive response or 635 mg has been administered. 

Hypertonic sodium chloride

All Hypertonic sodium chloride