Foradil - Formoterol (eformoterol) fumarate

Antimuscarinic bronchodilator.

• Over 18 years for maintenance of COPD: by inhalation of powder, one capsule, once daily.

Long-acting selective beta2 agonist with corticosteroid.

Prophylaxis of moderate-to-severe asthma for Aloflute® 25/125 by inhalation of aerosol
Adult: 2 inhalations twice daily.

Prophylaxis of moderate-to-severe asthma for Aloflute® 25/250 by inhalation of aerosol
Adult: 2 inhalations twice daily.

Long-acting selective beta2 agonist with long-acting muscarinic antagonist.

Adult: one inhalation twice daily. 

Antimuscarinic bronchodilator.

• Over 18 years: by inhalation of powder, 375 mcg (1 inhalation), twice daily.

Short-acting selective beta2 agonist.

For acute bronchospasm, Salbulin Novolizer® by inhalation of powder
Adult: Initially 100–200 micrograms, up to 800 micrograms daily for persistent symptoms.

For prophylaxis of allergen- or exercise-induced bronchospasm, Salbulin Novolizer® by inhalation of powder
Adult: 200 micrograms.

Short-acting selective beta2 agonist.

Oral
(Please note, inhalation route preferred over oral route in children.)
• Child 1 month–1 year: 100 mcg/kg (maximum 2 mg) 3–4 times daily
• Child 2–5 years: 1–2 mg, 3–4 times daily
• Child 6–11 years: 2 mg, 3–4 times daily
• Child 12–17 years: 2–4 mg, 3–4 times daily
• Over 18 years: 4 mg (elderly and sensitive patients initially 2 mg), 3–4 times daily, with a maximum single dose of 8 mg (but unlikely to provide much extra benefit or to be tolerated).

Moderate to severe or life-threatening acute asthma, treated by inhalation of nebulised solution. Give via a large volume spacer, and via a close-fitting face mask in children under 3 years.
• Child 1 month–4 years: 2.5 mg, repeat every 20–30 minutes or when required.
• Child 5–11 years: 2.5–5 mg, repeat every 20–30 minutes or when required.
• Over 12 years: 5 mg, repeat every 20–30 minutes or when required.

Long-acting selective beta2 agonist.

Reversible airways obstruction in patients requiring long-term regular bronchodilator therapy
Nocturnal asthma in patients requiring long-term regular bronchodilator therapy
Prophylaxis of exercise-induced bronchospasm in patients requiring long-term regular bronchodilator therapy
Chronic asthma in patients who regularly use an inhaled corticosteroid
By inhalation of powder:
• Child 6-11 years: 12 mcg twice daily should be sufficient for the majority of children, particularly for younger age-groups. Higher doses should be used rarely, and only when control is not maintained on the lower dose.
• Child 12-17 years: 12 mcg twice daily. Dose may be increased in more severe airway obstruction to 24 mcg twice daily, which should be sufficient for the majority of children, particularly for younger age-groups. Higher doses should be used rarely, and only when control is not maintained on the lower dose.
• Adult: 12 mcg twice daily. Dose may be increased in more severe airway obstruction to 24 mcg twice daily.

By inhalation of aerosol:
• Child 12-17 years: 12 mcg twice daily. Dose may be increased in more severe airway obstruction to 24 mcg twice daily, which should be sufficient for the majority of children, particularly for younger age-groups. Higher doses should be used rarely, and only when control is not maintained on the lower dose.
• Adult: 12 mcg twice daily, dose may be increased in more severe airway obstruction; increased to 24 mcg twice daily.

COPD
By inhalation of powder
• Adult: 12 mcg twice daily

By inhalation of aerosol
• Adult: 12 mcg twice daily (maximum per dose 24 mcg). If required, additional doses up to a maximum of 48 mcg per day can be taken.

Long-acting muscarinic antagonist, Long-acting beta 2 agonist.

Adult: two inhalations twice daily.

Long-acting selective beta2 agonist.

Oxis
By inhalation of powder for chronic asthma
• 6–17 years: 6–12 micrograms 1–2 times a day (max. per dose 12 micrograms), occasionally doses up to the maximum daily may be needed, reassess treatment if additional doses required on more than 2 days a week; maximum 48 micrograms per day.
• Adult: 6–12 micrograms 1–2 times a day, increased if necessary up to 24 micrograms twice daily (max. per dose 36 micrograms), occasionally doses up to the maximum daily may be needed, reassess treatment if additional doses required on more than 2 days a week; maximum 72 micrograms per day.

By inhalation of powder for relief of bronchospasm
• Over 6 years: 6–12 mcg up to twice daily

By inhalation of powder for prophylaxis of exercise-induced asthma
• Over 6 years: 6–12 mcg before exercise
• Adult: 12 mcg before exercise

By inhalation powder for COPD
• Adult: 12 micrograms 1–2 times a day (max. per dose 24 micrograms), for symptom relief additional doses up to maximum daily dose can be taken; maximum 48 micrograms per day.

Long-acting selective beta2 agonist.

• Over 18 years by inhalation: 5 mcg (2 puffs), once daily.

Long-acting muscarinic receptor antagonist, long-acting selective beta2 agonist with corticosteroid.

Trimbow 87/5/9 for moderate to severe COPD or asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow 172/5/9 for asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow NEXThaler 88/5/9 for moderate to severe COPD 
Adult: 2 inhalations twice daily.

Long acting muscarinic antagonist, long-acting beta 2 agonist and inhaled corticosteroid.

Two inhalations twice daily