Respiratory Handbook
For UK audiences

The professional's guide to product selection

Ryaltris - Mometasone furoate with olopatadine hydrochloride
Nasal preparations Corticosteroids Antihistamines Non-sedating antihistamines Glenmark Pharmaceuticals Europe Ltd.

Ryaltris - Mometasone furoate with olopatadine hydrochloride

For treatment of moderate to severe nasal symptoms associated with allergic rhinitis in adults and adolescents of 12 years of age and older.

  • Adults and adolescents of 12 years of age and older: two actuations into each nostril, twice daily

Indications

For treatment of moderate to severe nasal symptoms associated with allergic rhinitis.

Preparations Available

Spray

Sizes Available

Ryaltris 25 mcg/ 600 mcg per actuation, 240 doses per bottle 

Price

Nasal preparations

All Nasal preparations
Budesonide - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Budesonide - AAH Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis and nasal polyps by intranasal administration
• Over 6 years: 256 mcg once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved. Alternatively, 128 mcg twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Prophylaxis of asthma by nebulised suspension
• Child 6 months–11 years: 125–500 mcg twice daily, dose to be adjusted as required. Maximum 2 mg per day.
• Over 12 years: initially 0.25–1 mg twice daily, dose to be adjusted as required. Maximum 2 mg per day.

Budesonide - Alliance Healthcare (Distribution) Ltd
Alliance Healthcare

Budesonide - Alliance Healthcare (Distribution) Ltd

Prophylaxis and treatment of allergic rhinitis and nasal polyps by intranasal administration
• Over 6 years: 256 mcg once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved. Alternatively, 128 mcg twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Prophylaxis of asthma by nebulised suspension
• Child 6 months–11 years: 125–500 mcg twice daily, dose to be adjusted as required. Maximum 2 mg per day.
• Over 12 years: initially 0.25–1 mg twice daily, dose to be adjusted as required. Maximum 2 mg per day.

Prophylaxis of mild to moderate asthma by inhalation of powder
• Child 6 months–11 years: 200–400 micrograms once daily, dose to be given in the evening.
• Over 12 years: 200–400 micrograms once daily (max. per dose 800 micrograms), dose to be given in the evening.

Prophylaxis of asthma by inhalation of powder
• Child 6 months–11 years: 100–400 micrograms twice daily, dose to be adjusted as necessary.
• Over 12 years: 100–800 micrograms twice daily, dose to be adjusted as necessary.

Prophylaxis as treatment of allergic and vasomotor rhinitis by intranasal administration
• Child 6-17 years: 256 micrograms once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved, alternatively 128 micrograms twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.
• Adult: 256 micrograms once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved, alternatively 128 micrograms twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Dymista - Fluticasone with azelastine
Viatrus UK Healthcare Ltd

Dymista - Fluticasone with azelastine

For allergic rhinitis
• Over 12 years: one spray twice daily, dose to be administered into each nostril.

Mometasone furoate - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Mometasone furoate - AAH Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Mometasone furoate - Alliance Healthcare (Distribution) Ltd
Alliance Healthcare

Mometasone furoate - Alliance Healthcare (Distribution) Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Mometasone furoate - Almus Pharmaceuticals Ltd
Almus

Mometasone furoate - Almus Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Corticosteroids

All Corticosteroids
Budesonide - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Budesonide - AAH Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis and nasal polyps by intranasal administration
• Over 6 years: 256 mcg once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved. Alternatively, 128 mcg twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Prophylaxis of asthma by nebulised suspension
• Child 6 months–11 years: 125–500 mcg twice daily, dose to be adjusted as required. Maximum 2 mg per day.
• Over 12 years: initially 0.25–1 mg twice daily, dose to be adjusted as required. Maximum 2 mg per day.

Budesonide - Alliance Healthcare (Distribution) Ltd
Alliance Healthcare

Budesonide - Alliance Healthcare (Distribution) Ltd

Prophylaxis and treatment of allergic rhinitis and nasal polyps by intranasal administration
• Over 6 years: 256 mcg once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved. Alternatively, 128 mcg twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Prophylaxis of asthma by nebulised suspension
• Child 6 months–11 years: 125–500 mcg twice daily, dose to be adjusted as required. Maximum 2 mg per day.
• Over 12 years: initially 0.25–1 mg twice daily, dose to be adjusted as required. Maximum 2 mg per day.

Prophylaxis of mild to moderate asthma by inhalation of powder
• Child 6 months–11 years: 200–400 micrograms once daily, dose to be given in the evening.
• Over 12 years: 200–400 micrograms once daily (max. per dose 800 micrograms), dose to be given in the evening.

Prophylaxis of asthma by inhalation of powder
• Child 6 months–11 years: 100–400 micrograms twice daily, dose to be adjusted as necessary.
• Over 12 years: 100–800 micrograms twice daily, dose to be adjusted as necessary.

Prophylaxis as treatment of allergic and vasomotor rhinitis by intranasal administration
• Child 6-17 years: 256 micrograms once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved, alternatively 128 micrograms twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.
• Adult: 256 micrograms once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved, alternatively 128 micrograms twice daily, to be administered as 1 spray into each nostril in the morning and in the evening, reduce dose when control achieved.

Dymista - Fluticasone with azelastine
Viatrus UK Healthcare Ltd

Dymista - Fluticasone with azelastine

For allergic rhinitis
• Over 12 years: one spray twice daily, dose to be administered into each nostril.

Mometasone furoate - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Mometasone furoate - AAH Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Mometasone furoate - Alliance Healthcare (Distribution) Ltd
Alliance Healthcare

Mometasone furoate - Alliance Healthcare (Distribution) Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Mometasone furoate - Almus Pharmaceuticals Ltd
Almus

Mometasone furoate - Almus Pharmaceuticals Ltd

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg daily when controlled.

Management of nasal polyps by intranasal administration
• Adult: initially 100 mcg daily for five to six weeks, dose into each nostril, then increased if necessary to 100 mcg twice daily. Consider alternative if no improvement after five to six weeks. Reduce when controlled.

Antihistamines

All Antihistamines
Acrivastine - AAH Pharmaceuticals
AAH Pharmaceuticals

Acrivastine - AAH Pharmaceuticals

Non-sedating antihistamine.

Adult and child over 12 years: 8 mg, 3 times daily.

Chlorphenamine maleate - RX Farma
RX Farma

Chlorphenamine maleate - RX Farma

Sedating antihistamine.

By mouth for symptomatic relief of allergy such as hay fever, urticaria, food allergy, drug reactions, relief of itch associated with chickenpox.


• Child 1–23 months: 1 mg, twice daily.
• Child 2–5 years: 1 mg, every 4–6 hours, maximum 6 mg daily.
• Child 6–11 years: 2 mg, every 4–6 hours, maximum 12 mg daily.
• Over 12 years: 4 mg, every 4–6 hours, maximum 24 mg daily
• Elderly: 4 mg, every 4–6 hours, maximum 12 mg daily.


Emergency treatment of anaphylactic reactions or symptomatic relief of allergy by intramuscular injection or by intravenous injection over 1 minute.
• Child 1–5 months: 250 mcg/kg (maximum per dose 2.5 mg), max 4 doses daily
• Child 6 months–5 years: 2.5 mg, maximum 4 doses per day.
• Child 6–11 years: 5 mg, maximum 4 doses per day.
• Over 12 years: 10 mg, maximum 4 doses per day.

Desloratadine - Viatrus
Viatrus UK Healthcare Ltd

Desloratadine - Viatrus

Non-sedating antihistamine.

• Child 1–5 years: 1.25 mg once daily.
• Child 6–11 years: 2.5 mg once daily.
• Over 12 years: 5 mg once daily.

Fexofenadine hydrochloride - Noumed Life Sciences
Noumed Life Sciences

Fexofenadine hydrochloride - Noumed Life Sciences

Non-sedating antihistamine.

Seasonal allergic rhinitis
• Child 6–11 years: 30 mg, twice daily.
• Over 12 years: 120 mg, once daily.

Piriton - Chlorphenamine maleate
Haleon

Piriton - Chlorphenamine maleate

Sedating antihistamine.

By mouth for symptomatic relief of allergy such as hay fever, urticaria, food allergy, drug reactions, relief of itch associated with chickenpox.


• Child 1–23 months: 1 mg, twice daily.
• Child 2–5 years: 1 mg, every 4–6 hours, maximum 6 mg daily.
• Child 6–11 years: 2 mg, every 4–6 hours, maximum 12 mg daily.
• Over 12 years: 4 mg, every 4–6 hours, maximum 24 mg daily
• Elderly: 4 mg, every 4–6 hours, maximum 12 mg daily.


Emergency treatment of anaphylactic reactions or symptomatic relief of allergy by intramuscular injection or by intravenous injection over 1 minute.
• Child 1–5 months: 250 mcg/kg (maximum per dose 2.5 mg), max 4 doses daily
• Child 6 months–5 years: 2.5 mg, maximum 4 doses per day.
• Child 6–11 years: 5 mg, maximum 4 doses per day.
• Over 12 years: 10 mg, maximum 4 doses per day.

Rhinolast - Azelastine Hydrochloride
Viatrus UK Healthcare Ltd

Rhinolast - Azelastine Hydrochloride

Non-sedating antihistamine.

Over 6 years old: one spray twice daily to be administered in each nostril.

Non-sedating antihistamines

All Non-sedating antihistamines