Respiratory Handbook
For UK audiences

The professional's guide to product selection

Erdotin - Erdosteine
Mucolytics Erdosteine Galen

Erdotin - Erdosteine

Mucolytic to facilitate expectoration by reducing sputum viscosity.

• Over 18 years: 300 mg, twice daily for up to 10 days.

Indications

For symptomatic treatment of acute exacerbations of chronic bronchitis.

The Scottish Medicines Consortium stated in October 2007 that erdosteine (Erdotin) is not recommended for the symptomatic treatment of acute exacerbations of chronic bronchitis. For additional information see: https://www.scottishmedicines.org.uk/medicines-advice/erdosteine-300mg-capsules-erdotin-fullsubmission-41507/

Contraindications

Manufactorer recomments to avoid use in te case of hepatic or renal impairment or pregnancy and breast feeding. 

Preparations Available

Capsules

Sizes Available

Capsules
Erdotin capsules, 300 mg, 20 pack

Price

Mucolytics

All Mucolytics
Carbocisteine - AAH Pharmaceuticals Ltd
AAH Pharmaceuticals

Carbocisteine - AAH Pharmaceuticals Ltd

Reduction of sputum viscosity. 

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Accord Healthcare Ltd
Accord Healthcare

Carbocisteine - Accord Healthcare Ltd

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Esteve
Esteve

Carbocisteine - Esteve

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Typharm
Typharm

Carbocisteine - Typharm

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Carbocisteine - Viatrus
Viatrus UK Healthcare Ltd

Carbocisteine - Viatrus

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Osmohale - Mannitol - Chapper Healthcare
Chapper Healthcare

Osmohale - Mannitol - Chapper Healthcare

Mucolytic 

Osmohale is used for an indirect osmotic bronchial challenge test which can be used to identify bronchial hyperresponsiveness, a clinical feature of some respiratory conditions such as asthma.

Contraindications: Use with caution in renal impairment and to avoid in pregnancy. The Osmohale test should not be used in patients below 6 years of age due to their inability to provide reproducible spirometric measurements.

There is limited information on the use of Osmohale in patients 6-18 years of age therefore Osmohale is not recommended in this population.

Dose: See manufacturers’ instructions for more information. The test should be repeated until the patient has a positive response or 635 mg has been administered.